Preventive effects of dentifrice containing 5000ppm fluoride, against dental erosion by orange juice in situ
Study Objective: To evaluate the effectiveness of a dentifrice with 5000ppm fluoride in preventing dental erosion by orange juice in situ in comparison to a control dentifrice with 1450ppm fluoride.
Methods: This was a double-blind and randomized clinical study with a cross-over design. Sixteen subjects wore an intra-oral appliance containing two enamel disks with an exposed surface of approximately 2 × 5 mm. Enamel disks in the study group were treated with a dentifrice with 5000 ppm fluoride and in the control group with 1450 ppm fluoride. The subjects rinsed with slurries of study dentifrices for one minute before immersing the enamel disks in 250 ml orange Juice four times in an 8-hour period daily. The treatment procedure was repeated for three 5-day phases for each dentifrice. Enamel erosion was measured after each 5-day treatment phase using a focus-variation 3D scanning microscopy. Medians and inter-quartile ranges (IQR) of mean erosion depth were compared between the groups.
Source: Journal of Dentistry