A Systematic Review and Meta-Analysis of Asthma and Caries
The review shows there is inconclusive evidence suggesting a possible association of asthma with increased risk of caries. The authors conducted a systematic review and meta-analysis to synthesize the evidence on the relation between asthma and caries. They performed an Ovid Medline (US National Library of Medicine) database search of literature published from 1950 through May 2010 using the Medical Subject Headings “asthma” and “caries.” Summary effect estimates were calculated with fixed- and random-effects models, and determinants of heterogeneity were studied in meta-regression analysis. The meta-analysis was based on 11 articles providing estimates of the effect of asthma on primary dentition and 14 articles on permanent dentition. Summary effect estimates for the relation between asthma and caries